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67 Firebird is my dream car sm [2008-11-18]
Very similar to the Camaro. My dad had a 67 Firebird when I was younger and sold it when I was about 13 so my brother and I wouldn't be able to fight over it when we could drive. It got wrecked about 2 years later
A mother's dream! My children are young so (sm) [2008-10-29]
right now they say sweet things, well at least my 8 year old does...lol. I only dream that when they are your daughter's age they will think that highly of me :-) Congratulations!
Right, and I haven't said we are licensed to continue living in it (sm) [2008-10-16]
But guess what? I need to lose some weight! Do you think if people on the street start pointing at me and telling me to get myself under control that I am going to do it? No! If God wants me to change something, he will convict me in my own heart and let me know it. I don't need YOU to tell me, nor does anyone else. Can you not see that?
We are living in a sad world. [2008-10-15]
//
We have been living in ... [2008-10-13]
the me me me society where everything is now now now. DH and me cut up credit cards and paid off debt for the last 3-4 years instead of remodeling the house, buying new clothes/cars/toys.
I live in a $60,000 house that many people turned their nose up at because it wasn't an McMansion. Well we are about two years from paying it off without any help from anyone and those that turned their nose up at us are in foreclosure right now.
I had a feeling the stock market was going to crater - just didn't know how bad. I'm doing everything I can to keep my job and make the most of it. Now is not the time to go job-hopping.
Time for folks to live within their means and businesses/corporations need to realize that slow and steady growth isn't bad - its better then the alternative of not even being in business.
Finally I think we need to STOP rescuing this fat cats that make these stupid decisions that bankrupt these companies and put 1000's out of work. Make them return their golden parachutes and live like the common man. Same goes for salaries for actors/actresses and sports figures.
As an MT, I feel I've been living in a "recession" or - sm [2008-10-13]
a 'depression' for years already, not just recently. The only thing that's different for me now is how far my 401K has nosedived. When it happened after 9/11, I at least had the knowledge that I was still putting funds in, and my employer was matching those funds, and the mutual fund was buying more stocks with it at discount prices.
But this time around, the 401K has several more strikes against it:
- It still hadn't recovered to where it would have been if 9/11 had never happened.
- I haven't been able to fund it for the last three years, and as a result there is no employer input, either.
So what's changed for me now, is a real fear that I'll be on the streets in my old age, even though I'll still have to work forever. I was counting on money from my 401K to help make up the difference when my Social Security and work paycheck are not quite enough to live on. (And they WON'T be, especially if MT pay continues to be stagated or declining, as it is now.)
So at this point, I would say there really isn't any way to 'cope' - I'm already working as hard and as many hours as I can, and doing without everything but the most basic needs. So at this point, all that's left is to try to hope that something will change for the better in the years to come.
no but I always dream about a snake biting [2008-05-08]
different situations but the snake ALWAYS at least breaks the skin, no matter how much I try to protect him. :(
I once had a dream that my dog got killed - sm [2008-05-08]
and a week later to the day, she did. And it happened exactly like in my dream.
what i think is there are too many people living [2008-04-23]
what is good to one person, may not be to another but a free ride may be a lot of fun to some.
i don't sit and worry about it.... i just think it is incredibly sad the way i've seen it work so well for someone who doesn't even deserve it and works so slow for someone who does.
Grilled - I Dream of Jeanie or Bewitched. nm [2008-04-13]
Hi!
Not if they are legally living here or if [2008-04-11]
they have become citizens. That is why Carly could not compete 2 years ago when she made the top 24. Her paperwork had not yet gone through.
Anyone out there living in Maine? SM [2008-04-11]
An old boyfriend, who is now a minister lives in Bath, Maine. Can you tell me where it is located and something about it? I would appreciate it. I was thinking of maybe visiting his church.
Any kids with wife#2 are living at home and being [2008-04-03]
Kids should not expect to college paid for, so hubby should not pay for college for kidswith wife#2 since he did not pay for college for kids with wife #1.
I agree. I posted below about living in the battle zone - [2008-03-24]
If my parents would have had counseling, I might have been given a better example of how to disagree constructively and carried that forward in my life. Counseling is for getting through anything, you name it. Divorce too.
(your kids might need a place to voice themselves other than you, too.)
I think I'm living with your husband's brother [2008-02-24]
I've got a very similar issue going on right now, too, so I'm very interested in hearing the responses. I don't know how old you are, but one of the biggest problems for me is that at 49, my body image is more comfortable having sex with wild abandon under the cover of darkness and that morning light (not to mention the sheet wrinkles, morning mouth, etc.) just don't let me feel relaxed enough for great sex (I might add that we've only been together about six months, and while being comfortable enough to ignore one's own body flaws may come, I'm not there yet). In our case, he does at least seem interested in the sex, with days full of flirtatious innuendo (he owns a ranch, so we see each other a good deal during the day), but somehow, he cannot drag himself to bed before 3:00 a.m. (and gets up at around 11-12) about an hour after I've finally given up waiting and gone upstairs (I'm an 8-9 riser).
This is a hard one not to take too personally, but if your husband has always been like this, it doesn't seem like it could suddenly be you. And, for what it's worth, there are many women who fall into the size 4 category (although I ain't one of them) who have the same issue, so it's not that weight loss/starvation will be this magical cure-all. As noted, I look forward to hearing from those who have gone through the same thing (and sorry for all the parentheses).
a girl can dream.. ;) [2008-02-19]
xx
Buying new living room furniture this weekend... [2008-01-31]
Can't wait!! :)
When do you get to live? When you start living and [2008-01-19]
x
Are we living in a big-brother nation [2008-01-14]
While I feel it was disrespectful from the student I feel it should have been handled differently. I don't believe the school should have been involved, since it didn't happen on school property or with school property. If I was the teacher I would have contacted the parents and talked to them and let them know how uncomfortable I feel about something that was written about me and let the parents handle how to discipline their own child. The school should have no say on how to discipline this child. What will the next step of the studen't personal life will the school decide to be involved in.
Keys - Son - Living with Daughter [2008-01-08]
However, why post if you were wrong and then defend yourself to the opinions that were posted???? I don My parents had an open door policy. No matter what, they stuck by my decisions. I moved out twice and moved back in before getting married when apartment life did not work out for whatever reason. I did not move out when I was 16 though as my parents were responsible for me until I was 18. Once I turned 18, they still let me move in and out and I also always had a key. I had a key to the house they lived in, and then I had a key to my Mom
I think there are more issues here than you want to admit. I think if you tried counseling instead of arguing with your son about a key, then you may get to the root of the problem. The fact that you won You are now telling him that his home is no longer his home by taking the key away.
I think that it is just understood that once one moves out on their own that the original home is not their home, but they are still welcome. I don
When we bought our first home and had children, we became a team. We are a family and even though my husband and I pay the bills, we do tell our children that this is our home. They help with chores and that
I don I just think you may want to consider some help from something other than this board. You may want to try a church or a counselor to help you with your teenager. I
My Mom used to say You are born, but you In other words, anyone here can state their opinions on the rearing of their own children, but not until you die can you say that never happened to me! My Mom would say this when I would give judgemental remarks of others. This was to open my eyes to the fact that the very same thing I am talking about could happen to me!
Lots of luck and love to you! I certainly hope there is a way to keep an even ground with your son. Blood is thicker than water...
Bigger issue - a 16 year old living withi a 29 year old and liability [2008-01-07]
Are you still not responsible for him until he is 18, how can he tell you where he will live? Unless he emancipates himself and he does something wrong, can they go against you since you are his mother and legally responsible for him? I worry more about him living with a 29 year old sister rather than returning a house key to me that is a bigger issue.
what's wrong with living [2008-01-07]
with a 29-year-old? I was married with two kids, owned a house, etc. when I was 29. It is not like he is going to live with a 19 or 21-year-old who might not be that mature or responsible.
After 6 months of looking and living [2008-01-05]
like a pauper I am now pretty happy in the new job I have. I am also behind on every bill in the house! Has anyone used a credit counseling service to help them with debt and paying off everything to get their credit back on track? I want to use a legitimate company and not worsen my situation more than it is. Thanks everyone.
I'm telling you after years of living with the same family - they figure things out! sm [2008-01-03]
For example, he knows that if I am going somewhere with the kids, he probably canI want to go!!
LOL - I used to dream of Kramer when I was pregnant LOL (nm) [2008-01-02]
x
Live in WI [2008-11-18]
I live in northern WI and it is only my husband and Iin the household. I think we spend about 75 a week. We used to spend less living in south-central WI, but found groceries are more expensive up here.....
I try to use coupons whenever possible. I definitely get more bang for my buck...
I'm embarrassed to say this, but [2008-11-18]
we usually eat out at least 3 if not 4 nights a week. Always eat out on Fridays and Saturdays and then usually Tuesday and Thursday nights.
I generally cook a large family meal on Sunday with enough leftovers to last through Monday. Tuesday night we either order in and Wednesdays we have breakfast for dinner -- my kids love that one. Thursdays we usually order in because it
We usually eat out Friday nights because we go to get groceries (I don Saturday we
We When it was a 15-minute drive to town, I planned our meals ahead of time and usually only ordered once a week or once every 2 weeks and we only ate out on Saturdays. We seemed to have picked up these extra 2 nights of ordering in out of convenience (a nicer word than laziness).
Oh the cost -- I have 3 kids and a hubby. On the nights we order in, we spend about $25 to $30 (saving because of no drinks or appetizers). When we eat out, the bill is usually around $50. So altogether, I guess I spend about $155 a week on eating out -- WOW/YIKES! Thanks for making me realize that. I think it
YEAH baby!! Me too. sm [2008-11-18]
About 10 years ago I bought a Honda HX with prototype gas-efficient trannie, light wheels, no frills. That puppy would still be with me if not for the prototype trannie pretty much fizzled on most of the HXs but I milked mine for as long as possible.
Ex had a Prelude, same year (99). He loved the car and took great care of it. Gas was killing him though (uses it to drive and travels a bit). He wanted to keep it in the family so he sold it to me. I drive about 5000 miles a year, if that. Amost 300,000 miles on that one and what a dream it is!!!
He bought a new Civic. Another SWEET car.
My son has a 1990 Accord, bought it used with less than 100,000 miles about 3 years ago. We've put some money into it, mostly cosmetic and just catching stuff up, but it runs like new.
My Civic was actually built in US, so I didn't feel too guilty, but how many years have US automakers had to see the writing on the wall? I'm sorry, but I like keeping a car forever. No car payments are great. Honda fits that mold.
My DH drives a Chevy Malibu Maxx... [2008-11-17]
I have a 2005 Buick LeSabre and we also have an older Ford Explorer that DH kept to use for hauling stuff.....
I've never had anything but an American made car........... LOL, I'm not exactly a car salesperson's dream customer........ I keep my cars forever......
1972 Plymouth Duster
1984 Buick Skyhawk
1996 Buick Century
2005 Buick Skyhawk..........
only 4 cars in over 30 years......
I used to feel the same way, but [2008-11-17]
my family loves my e-cards, which I have only sent for birthdays and Mother's Day (also sent flowers to Mom). They know that I don't get out to shop much, though. I actually bought a subscription to Doozy Cards because at that time we only had one car, and with us living so far from everything and wanting to spend what time I could with my family, it seemed senseless to have to go out at night after hubby got home from work.
For Christmas I would send paper cards. To OP, I do not think handing them is tacky. I've heard others say that it is, but I think it is the thought that counts.
My first car was a 1967 red Camaro [2008-11-17]
now a classic, got up to 86,000 miles only replacing the water pump, then my husband wrecked it. I am still mad at him for that one. I now have a 1995 3/4 ton chevy truck, paid for, have 166,000 miles on it, been a very good vehicle - thank you all GM workers. It tows and pull horses like a dream, don't even know anything is back there. Hate cars now.
What a kind post..sm [2008-11-16]
I am a very caring person. I have an extreme soft spot for animals. Dogs especially. I have a stray that was apparently dropped off here, and he is a big dog. My husband said he is a Catahoula Kur dog. He is such a sweetheart, but he can aggravate you to death. He is bad about running in the house when you open the door, and he is so big I can't hardly get him out. I have had to literally drag him by his feet out the house. As annoying as that is I can't be mean to him. I feed him everyday and talk to him and pet him. I don't need another dog but I feel so bad for him. I feel like he needs a home and and someone to care for him. So I guess I am stuck with him. I don't have the heart to take him to the pound. I just can't do that. My husband loves dogs too but he says I am just ridiculous. He thinks I treat them like people. I just see it as they are living breathing animals and they feel. There are some people who say I wouldn't feed the dogs that belonged to the guy. I could NEVER let those dogs starve. That is the thing, I think the guy knows what a softie I am and he knows I will not let them do without and he takes advantage of it.
This guy, by the way, is single and fully capable financially of feeding and caring for the dogs. He just is lazy and doesn't want to be bothered when he gets home from work. It isn't my place to care for his dogs but I can't let them starve either. I don't know. I am caught between a rock and a hard spot.
How many of you have a backup plan [2008-11-13]
if your spouse were to lose their job? Assuming the MT rate of pay isn I don
We have no backup plan. My in-laws already have their other son (and family of 4) living with them due to job loss. My family lives in another state altogether. I don I just don Should we have some sort of plan in place? Do most people? Our savings has dwindled to nothing this past year with all the increased expenses and we have cut back all we can. There's nothing else to cut other than house/cars/utilities.
Let's get to know pit bulls...sm [2008-11-09]
A lot of people on here I am sure do not own a pit bull. It is hard to know the breed when you aren't around them on a day to day basis. I would just like to share some traits of pit bulls.
Pits are robust. They are active and love to play. They are a smart breed of dog too. I guess you could say they are roughnecks. They will do anything to please their owners and want to be a big ole lap dog. Oh yeah they will and mine does (all 70 pounds) climb up in your lap wanting to be nurtured. LOL.
If I had to describe their personality I would say first of all contrary to all the media hype and hysteria of pits, the dogfighting community (by the way I do not condone dogfighting) did not breed pit bulls to be human aggressive. They wanted a dog they could work with in the fighting arena and not have to worry about these dogs attacking them or other people watching this sport. (which is unscrupulous but just trying to explain this is how they were bred). A lot of pit bulls are so happy on meeting owners friends they don that some people who get them worry they won't make a good guard dog because some happily greet strangers. The protective instinct a pit has usually won't surface until they are about a year old. I would say they want to be the center of attention. They are very self confident dogs.
I have to say pits can be funny. One reason is pits have some of the most expressive faces.
Sometimes though you may have a perfectly nice pup which will grow up to be mean because he was encouraged to be mean. Raised to be mean.
If pit bulls could choose their owners instead of the other way around then I would say a pit would choose an owner with high spirits and a joy of living. Good owners of pits are able to handle their dogs.
A pits character traits seem to be contradictory in that they are strong but sensitive; rowdy but gentle; outgoing but devoted; easily fired up but highly trainable; mischevious but sensible; energetic yet serene; peaceful but always alert. All these describe the pit bull.
nursing home decision [2008-11-09]
I am living this as we speak. My father died in March of 2007. My mother became bedridden in June 2007. I had hospice come in to assist, Home Health and Hospice to be exact, and they are wonderful. They actually have their own private nursing home-type facility in the next town over. With hospice, on an occasional basis and when a bed is available, they offer the caregiver a 5-day respite at their facility. After momma went for the first time she was offered a bed there and I immediately accepted. The facility is very small and only for the 3HC clientele, with only 12 private rooms divided into 2 sides - one side with 6 beds for the terminal clients and one side with 6 beds for residential clients. Momma was able to stay on the residential side for 7 months; however, her condition was stable and Medicare would no longer pay the fee. Momma came home after that and I have again been her primary caregiver since January of this year. She is contractured, bedridden, and rarely speaks or opens her eyes. I do have a sitter that works during the daytime hours M-F so that I can actually work, run errands when I need to, and get the kids to and from school because otherwise I cannot leave the house at all because momma cannot be left alone.
I feel blessed to have found this line of work not quite 6 years ago. I have a 4-1/2 year old and a 6 year old and momma to care for so working from home has been a lifesaver.
I, too, made the promise to momma that I would not put her in a nursing home and I will stand by that. Itcare most of the public places provide.
It's a tough decision to make - even tougher if there aren't funds available like there are in our case (thanks to my great daddy) to pay for the sitter to come in and assist. But when the sitter isn't here, the kids and I must be. For the most part they understand, but sometimes they really just want to go somewhere or to the park or to McDonalds and we just can't do it. It's a huge personal sacrifice for your entire family to make to keep a parent at home. The decision isn't always just personal, though. It can be financial, too.
You will make the right decision for whatever your situation is. Whatever you decide to do, just know that your parent respects you enough to make that decision for them and that they love you.
Best of luck to you honey... hugzzzzz
nursing home - hardest decision ever sm [2008-11-09]
I had also made those promises to my folks, Dad was kept home on hospice 14 months, he had suffered brain damage from not being found for hours and was awful to all of us but we managed with a hospital bed, hospice and nurses, however, my whole family fell apart, fighting, etc., until he fell so many times and was so sick, we called 911 one night for help and hospice literally threw us out of the program. You are supposed to call them (in my state anyway) and they will sit with you while you watch them take their last breaths. Could not go through with that. Then we had no choice but nursing home, they took every cent they could get their hands on without touching my momshow up to check on them. Sometimes theyassisted living scenario, and after they clean out the bank book, they put them in a nursing home anyway, so thatsandwich generation between what to do with the parent and if you have kids, what is best for them. Itshow up and if you don it's tough to walk that walk. Take care, hopefully you will make the right decision. In some states you can have her in a nursing home and if she qualifies, you can also have hospice go in there for special care such as you desire for her comfort. Good luck, know we are all thinking of you.
You are absolutely right, he [2008-11-08]
could have done any of a number of things to causeA PIT BULL dog to attack and kill him. He could have yelled at the TV. He could have stepped on one of their feet. He could have fallen down. We donno pet should ever be capable of killing a human with whom it shares a home. Other breeds recognize their master and other humans in their living spaceand take their rightful place. Most good, smartcompanion dogs would have recognized this manThe instinct of these dogs to attack overcomes them and they can This breed should never be kept as pets.
You should visit the web site I posted and click on the tab about pit bull owners. I find it very interesting that you have used the same phrases that most owners use to defend the breed.
Can you name one desirable character trait that a pit bull has that you cannot find in any other dog?
Yes, and it was a very hard decision... [2008-11-08]
I had moved my mom in with me after she had surgery/went through rehab.. And I took care of her for 19 months. It was so hard. She had to go back in the hospital and I was fighting with my family at the same time for help... It was really overwhelming. She is still living but unfortunately my family moved her closer to them where she did not get the best care and was eventually moved again, further away from me to a facility that I can appreciate. She looks really well and I know that she is being taken care of. I miss her. I can not visit her as often as I would like but I know that she is being taken care of... It is a very hard decision that I can not say that I don I also contemplate on a daily basis if I made the right decision. A day never passes that I don
Actually raw/organic/natural is the best [2008-11-05]
But you do have to watch where the ingredients come from because like one of the posters said they can contract parasites just like humans could if they have bad meat. I've attached a link. I think if you start pets at a young age they will take to the raw food diet, but trying to start an adult cat is difficult.
http://www.living-foods.com/articles/rawpetfood.html
The 90210 episode is season 8, episode 3 - sm [2008-11-05]
I remember sometime last year when we were getting Rolling Stone magazine we got an issue with them all over the cover and a huge article inside, certainly coinciding with the release of It Won't Be Soon Before Long. I didn't know who they were then and let the magazine be thrown out. I could kick myself! haha.
A Meet and Greet?? Oh what a dream come true that would be!
My sons are 18 and 20. [2008-11-04]
One lives at college and the other is living at home while attending college. When they were both at home and under 18 I had the same rules as you, basically. During the week, except for their activity obligations of school, sports, scouts, they didnhang out time. It did help that their high school was in the next county, and most of their school friends lived some distance away. When girlfriends came along, life was a little different. My oldest dated a girl who lived down the street. My youngest dated a girl who lived a good 30-minute drive away. Lucky for me, their parents had the same rules for hanging out. It was pretty much weekends only. My boys accepted it all in stride. But I have to say that I've been pretty strict about their attitude all of their lives. Since they first began to speak, they learned not to give attitude to their parents. In return, we always treated them with respect. The few times that they did raise their voices as teenagers, our conversation came to an end, and their requests were denied with no chance for a reversal of that decision. Worked nicely. But, again, I have to say we were very lucky in that most of their friends weren't right in our neighborhood and their girlfriends had the same rules.
The payoff is that now as responsible young adults, they've developed a good work ethic. Even my son living at college does well managing his free time, and will be an RA in his dorm next year, partly because he's shown maturity and isn't goofing off at college. (And I'm glad not to have to pay all of the room and board! Hooray!)
Why does Walmart have so many automated registers?? (sm) [2008-11-03]
When they don't work at least 50% of the time and you have to wait for someone to come help you? Why can't they employee real living, breathing humans??
Awww I love 'zons! sm [2008-11-01]
I am down to budgies, but I did have an Indian ringneck parakeet for a long time, 2 in fact. I finally decided that she didn't have the life here that she needed and deserved, so I gave her to someone who has always been crazy about her. She is much happier and well loved. IRNs are not as teachable as an Amazon. They tend to be more calm and live in harmony with furkids. Plus, they are so large that no right-minded cat or dog would dare to challenge them. I know of a couple of 'zons who have put holes in cat's and dog's ears just for living.
You have to know that she is very attached to Birdie. I have a feeling, however, if someone was hurting you she'd do the same thing to them that she did to your jacket.
I am glad you spoil her, she is a lucky bird. So many people go into having a larger parrot and don't understand their habits and needs. This is why so many birds are abused and far too many of them can't recover from it. I'd be willing to bet she is beautifully fully feathered and a deep lime green. If her whole head is yellow, she is a double yellow head. If that is the case, they are known to be the best tempered of all the Amazons (and the most expensive in many places). Thanks for being a good birdie mom, we need more like you!
This is a hot topic and I need some opinoins. I have asthma and the lady downstairs..sm [2008-11-01]
in the apartment below me must smoke 4 packs a day. She never leaves the house and she just closets herself inside smoking all day long until about2 a.m. and then sleeps late. I can SMELL the minute she wakes up. I KNOW this is second hand smoke and I have been hospitalized three times in the last two years with bronchitis. I really cant afford to move. I have complained to the apartment manager about it and she basically said there is nothing she can do. I have canvassed the apartment and have blocked up every hole I can that this might be seeping through. Now that the colder weather is here, the windows are closed and it is even worse. I need bigger balls to deal with this and the DH is no help at all because it doesn but I feel that because my asthma is so bad and I am living with this in my home that he should step up with me on this issue. I have lived above this lady for 3 years and I am through.This lady knows my problem, I have THREE hepa filters running in my house and have given her a $500.00 ionic breeze quadra professional unit for her living room.Any good words?
So sorry - this is a tough one [2008-11-01]
I REALLY feel badly for you. This has got to be absolutely horrible for you to deal with, as there is not much that can be done, and it is hurting your health. There is only one thing you can do, and that is move. Is there some way you could find a way to do it? The problem with apartment living is that this could happen again, even if you do move, but don't know if it would be this bad. I truly feel your pain, I wish there was a more helpful suggestion to make.
Now that I live in town -- 3 [2008-10-31]
We In that time, I We have also asked another neighbor to dog-sit for the weekend and my other neighbor I I'm literally right around the corner from the grocery store, so it would be very hard for me to ask for an egg or milk, etc.
When we lived in the country, we only had 2 neighbors, but I the last things I borrowed from them were lemon juice and eggs.
When I first got married, though, I used to live right beside my grandma and just across from parents. We used to always call one another for a roll of toilet paper. I don I guess it was just part of the newlywed process for me (don't know about my parents and grandparents).
We had dinner at a very nice restaurant sm [2008-10-31]
and then went home and ate the top of the cake....not so great, but it was fun. We also watched our wedding video. We had a very small reception, no band or dancing, but the song I had the Time of My Life (from Dirty Dancing) was played over and over on our honeymoon, so danced in our living room to that song and well.......one thing led to another. It was very romantic.
How to get paw prints off polished furniture [2008-10-30]
I have a small mahogany chest next to my front door. My son's girlfriend's cat is living with us temporarily while his owner moves into her new house. She's a lovely cat, but she likes to hop up on the mahogany near the front door to see who is coming and going. She's left lots of paw prints on the shiny surface. I tried polishing with pledge. I tried cleaning with Pergo wood floor cleaner, and I've tried something called Cabinet Magic, a cleaner for wood cabinets. I've gotten a lot of the prints up, but there are a few still there. I've put a towel over the surface until Kitty moves to her own home this weekend. But how can I get those last smudgy prints off my shiny wood surface?
The Stink in Farts Controls Blood Pressure... [2008-10-30]
Amelia TomasLiveScience StaffLiveScience.com amelia Tomaslivescience Stafflivescience.com – Thu Oct 23, 3:21 pm ET
A smelly rotten-egg gas in farts controls blood pressure in mice, a new study finds.
The unpleasant aroma of the gas, called hydrogen sulfide (H2S), can be a little too familiar, as it is expelled by bacteria living in the human colon and eventually makes its way, well, out.
The new research found that cells lining miceno doubt produced in cells lining human blood vessels too, the researchers said.
Now that we know hydrogen sulfide said Johns Hopkins neuroscientist Solomon H. Snyder, M.D., a co-author of the study detailed in the Oct. 24th issue of the journal Science.
Snyder and his colleagues compared normal mice to mice that were missing a gene for an enzyme known as CSE, long suspected as being responsible for making hydrogen sulfide. As they measured hydrogen sulfide levels taken from tissues of the CSE-deficient mice, the scientists found that the gas was depleted in the cardiovascular systems of the altered mice. By contrast, normal mice had higher levels of the gas, thereby showing that hydrogen sulfide is naturally made by mammalian tissues using CSE.
Next, the mice were subjected to higher blood pressures comparable to serious hypertension in humans. Scientists had them respond to a chemical called methacholine that relaxes normal blood vessels. The blood vessels of the CSE-lacking mice hardly relaxed, indicating that hydrogen sulfide is a huge contender for regulating blood pressure.
Hydrogen sulfide is the most recently discovered member of a family of gasotransmitters, small molecules inside our bodies with important physiological functions.
This study is the first to reveal that the CSE enzyme that triggers hydrogen sulfide is activated itself in the same way as other enzymes when they trigger their respective gasotransmitter, such as a nitric oxide-forming enzyme that also regulates blood pressure, Dr. Snyder said.
Because gasotransmitters are common in mammals all over the evolutionary tree, these findings on the importance of hydrogen sulfide are thought to have broad applications to human diseases, such as diabetes and neurodegenerative diseases.
The research was supported by grants from the U.S. Public Health Service and the Canadian Institutes of Health Research as well as a Research Scientist Award.
A mother's dream! My children are young so (sm) [2008-10-29]
right now they say sweet things, well at least my 8 year old does...lol. I only dream that when they are your daughter's age they will think that highly of me :-) Congratulations!
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