Got anything else to go on?

U.S./Canadian Brand Names

• Adrenalin® Chloride
  
• AsthmaHaler® Mist [OTC]
  
• AsthmaNefrin® [OTC]
  
• Bronitin® Mist [OTC]
  
• Bronkaid® Mist [OTC]
  
• Epifrin®
  
• EpiPen®
  
• EpiPen® Jr
  
• Glaucon®
  
• microNefrin® [OTC]
  
• Primatene® Mist [OTC]
  
• Sus-Phrine®
  
• Vaponefrin® [OTC]

Therapeutic Category

• Adrenergic Agonist Agent

Use

Treatment of bronchospasm, anaphylactic reactions, cardiac arrest, and management of open-angle (chronic simple) glaucoma

Usual Dosage

  Bronchodilator:
  Children: S.C.: 10 mcg/kg (0.01 mL/kg of 1:1000) (single doses not to exceed 0.5 mg); injection suspension (1:200): 0.005 mL/kg/dose (0.025 mg/kg/dose) to a maximum of 0.15 mL (0.75 mg for single dose) every 8-12 hours
  Adults:
  I.M., S.C. (1:1000): 0.1-0.5 mg every 10-15 minutes to 4 hours
  Suspension (1:200) S.C.: 0.1-0.3 mL (0.5-1.5 mg)
  I.V.: 0.1-0.25 mg (single dose maximum: 1 mg)
  Cardiac arrest:
  Neonates: I.V. or intratracheal: 0.01-0.03 mg/kg (0.1-0.3 mL/kg of 1:10,000 solution) every 3-5 minutes as needed; dilute intratracheal doses in 1-2 mL of normal saline
  Infants and Children: Asystole or pulseless arrest:
  I.V., intraosseous: First dose: 0.01 mg/kg (0.1 mL/kg of a 1:10,000 solution); subsequent doses: 0.1 mg/kg (0.1 mL/kg of a 1:1000 solution); doses as high as 0.2 mg/kg may be effective; repeat every 3-5 minutes
  Intratracheal: 0.1 mg/kg (0.1 mL/kg of a 1:1000 solution); doses as high as 0.2 mg/kg may be effective
  Adults: Asystole:
  I.V.: 1 mg every 3-5 minutes; if this approach fails, alternative regimens include: Intermediate: 2-5 mg every 3-5 minutes; Escalating: 1 mg, 3 mg, 5 mg at 3-minute intervals; High: 0.1 mg/kg every 3-5 minutes
  Intratracheal: Although optimal dose is unknown, doses of 2-2.5 times the I.V. dose may be needed
  Bradycardia: Children:
  I.V.: 0.01 mg/kg (0.1 mL/kg of 1:10,000 solution) every 3-5 minutes as needed (maximum: 1 mg/10 mL)
  Intratracheal: 0.1 mg/kg (0.1 mL/kg of 1:1000 solution every 3-5 minutes); doses as high as 0.2 mg/kg may be effective
  Refractory hypotension (refractory to dopamine/dobutamine): I.V. infusion administration requires the use of an infusion pump:
  Children: Infusion rate 0.1-4 mcg/kg/minute
  Adults: I.V. infusion: 1 mg in 250 mL NS/D₅W at 0.1-1 mcg/kg/minute; titrate to desired effect
  Hypersensitivity reaction:
  Children: S.C.: 0.01 mg/kg every 15 minutes for 2 doses then every 4 hours as needed (single doses not to exceed 0.5 mg)
  Adults: I.M., S.C.: 0.2-0.5 mg every 20 minutes to 4 hours (single dose maximum: 1 mg)
  Nebulization:
  Children <2 years: 0.25 mL of 1:1000 diluted in 3 mL NS with treatments ordered individually
  Children >2 years and Adolescents: 0.5 mL of 1:1000 concentration diluted in 3 mL NS
  Children >2 years and Adults (racemic epinephrine):
  <10 kg: 2 mL of 1:8 dilution over 15 minutes every 1-4 hours
  10-15 kg: 2 mL of 1:6 dilution over 15 minutes every 1-4 hours
  15-20 kg: 2 mL of 1:4 dilution over 15 minutes every 1-4 hours
  >20 kg: 2 mL of 1:3 dilution over 15 minutes every 1-4 hours
  Adults: Instill 8-15 drops into nebulizer reservoirs; administer 1-3 inhalations 4-6 times/day
  Ophthalmic: Instill 1-2 drops in eye(s) once or twice daily
  Intranasal: Children ≥6 years and Adults: Apply locally as drops or spray or with sterile swab

Dosage Forms

  Aerosol, oral:
  Bitartrate (AsthmaHaler®, Bronitin®): 0.3 mg/spray [epinephrine base 0.16 mg/spray] (10 mL, 15 mL, 22.5 mL)
  Bronkaid®: 0.5% (10 mL, 15 mL, 22.5 mL)
  Primatene® Mist: 0.2 mg/spray (15 mL, 22.5 mL)
  Auto-injector:
  EpiPen®: 1 mg/mL [1:1000] (2 mL)
  EpiPen® Jr.: 0.5 mg/mL [1:2000] (2 mL)
  Solution:
  Inhalation:
  Adrenalin®: 1% [10 mg/mL, 1:100] (7.5 mL)
  Injection:
  Adrenalin®: 0.01 mg/mL [1:100,000] (5 mL); 0.1 mg/mL [1:10,000] (3 mL, 10 mL); 1 mg/mL [1:1000] (1 mL, 2 mL, 30 mL)
  Suspension (Sus-Phrine®): 5 mg/mL [1:200] (0.3 mL, 5 mL)
  Nasal (Adrenalin®): 0.1% [1 mg/mL, 1:1000] (30 mL)
  Ophthalmic, as hydrochloride (Epifrin®, Glaucon®): 0.1% (1 mL, 30 mL); 0.5% (15 mL); 1% (1 mL, 10 mL, 15 mL); 2% (10 mL, 15 mL)
  Topical (Adrenalin®): 0.1% [1 mg/mL, 1:1000] (10 mL, 30 mL)

• Epinephrine and s/l apo dace - Help!
  • could it be iopidine - stinkerbell
  • Might be Amphadase - sm - John
  • What's the procedure and where are you injected this combo? nm - wanderer
    • In the upper eyelid. - NM
  • Got anything else to go on? - Hayseed
    • It's the 'A' word that I need help with - .

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