Use
Treatment of patients with documented multidrug resistant aerobic gram-negative infection in which beta-lactam therapy is contraindicated; used for urinary tract infection, lower respiratory tract infections, septicemia, skin/skin structure infections, intra-abdominal infections and gynecological infections caused by susceptible Enterobacteriaceae, H. influenzae, and P. aeruginosa
Usual Dosage
Children >1 month: I.M., I.V.: 90-120 mg/kg/day divided every 6-8 hours
Cystic fibrosis: 50 mg/kg/dose every 6-8 hours (ie, up to 200 mg/kg/day); maximum: 6-8 g/day
Adults:
Urinary tract infection: I.M., I.V.: 500 mg to 1 g every 8-12 hours
Moderately severe systemic infections: 1 g I.V. or I.M. or 2 g I.V. every 8-12 hours
Severe systemic or life-threatening infections (especially caused by Pseudomonas aeruginosa): I.V.: 2 g every 6-8 hours; maximum: 8 g/day
Dosage Forms
Infusion, premixed: 1 g (50 mL); 2 g (50 mL)
Powder for injection: 500 mg (15 mL); 1 g (15 mL); 2 g (30 mL)
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